左西孟旦对慢性心衰患者心功能及N端脑钠肽前体的影响
Effects of levosimendan on cardiac function and N terminal brain natriuretic peptide in patients with chronic heart failure
吴岩松 1马丽娜 1赵振梅1
作者信息
- 1. 辽宁省营口市中心医院 营口 115000
- 折叠
摘要
目的：：探讨左西孟旦对慢性心力衰竭(CHF)急性加重期患者心功能及 N端脑钠肽前体水平的影响.方法：CHF患者55例,随机分为常规治疗组(25例)及左西孟旦(30例,常规治疗基础上加用左西孟旦),比较治疗前后患者心功能变化及 N端脑钠肽前体(NT－pro－BNP)的差异.结果：左西孟旦组的总有效率明显高于常规治疗组(P＜0．05),SV及 LVEF均较常规治疗组显著改善(P＜0．05)；NT－pro－BNP水平与常规治疗组比较有显著下降(P＜0．05).结论：左西孟旦可以明显改善 CHF患者的心功能,降低 NT－pro－BNP水平.
Abstract
Objective:To study the ef ects of levosimendan on cardiac function and the levels of N terminal brain natriuretic peptide (NT-pro-BNP)in patients with chronic heatr failure(CHF)in acute aggravation status.Methods:55 patitents with CHF in acute aggravation status were randomly divided into routine treatment group(n=25),levosimendan group(n=30,received levosimendan based on rouG tine treatment),The cardiac function and the lvels of NT-pro-BNP wre observed in al groups before and after treatment.Result:The total ef ective rate in the levosimendan group was higher than the routine treatment groupl(P<0.05),and the SV and LVEF were significantly improved than routine treatment group (P<0.05);there were significant decreased in the levels of NT-pro-BNP in the levoG simendan group with the routine treatment group(P<0.05).Conclusion:Levosimendan can improve cardiac function CHF patients,and reduce the levels of NT-pro-BNP.
关键词
慢性心衰/左西孟旦/N端脑钠肽前体Key words
Chronic heatr failure/Levosimendan/N terminal brain natriuretic peptide引用本文复制引用
出版年
2015
NETL
NSTL
万方数据