Based on gene therapy as a fundamental treatment for diseases,it brings new ideas and methods for the treatment of rheumatoid arthritis(RA).We review the relevant research advances of gene therapy for rheumatoid arthritis,including small interfering RNA(siRNA),micro RNA(miRNA),DNA,CRISPR/Cas9 system,deoxyribonuclease and some other technologies,providing reference ideas for the application of gene therapy in the field of RA and offering more effective and targeted treatment plans for the patients with RA.
关键词
类风湿关节炎/基因治疗/小干扰RNA/微小RNA/DNA折纸/CRISPR/Cas9系统
Key words
rheumatoid arthritis/gene therapy/small interfering RNA/micro RNA/DNA origami/CRISPR/Cas9 system