Autoclave is an important equipment for the production of composite materials,belonging to high temper-ature and high pressure equipment,widely used in aviation,aerospace,machinery,heat treatment,military indus-try and other industries.According to the characteristics of autoclaved tank,this paper introduces an effective cali-bration method involving temperature,pressure and vacuum leakage rate,and analyzes some key parameters in the use process,discusses the technical index requirements,the selection of standard and the determination of calibra-tion method,so as to determine an accurate and reliable traceability chain.