首页|从"络病-风药"理论探讨独活寄生汤治疗类风湿关节炎

从"络病-风药"理论探讨独活寄生汤治疗类风湿关节炎

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类风湿关节炎(RA)属中医"痹病"范畴,其发生、发展、转归与络病密切相关.本文通过分析类风湿关节炎微小血管新生的病理状态与络脉生理和络病病机特点,以络脉为其邪伏、邪发、邪伤及邪阻之所展开论述,可认为"络病"是其病理基础,络虚是其根本病机,风挟寒湿之邪内侵络脉为发病关键.基于"络病"理论和"风药"理论相关认识,从独活寄生汤为治风之剂视角认识其治疗类风湿关节炎的作用,并提出病变早期络脉郁滞、风药先行,中期络脉瘀塞、健脾化瘀,晚期络脉空虚、风引入肾,探讨独活寄生汤在病变不同时期风药与他药的组方原理,丰富独活寄生汤的组方配伍理论,扩展独活寄生汤的临床指导意义,为其临床应用提供参考.
Discussion on the treatment of rheumatoid arthritis with Duhuo Jisheng Decoction from the theories of collateral diseases and wind herbs
Rheumatoid arthritis belongs to the category of bi syndrome in traditional Chinese medicine,and its occurrence,development and prognosis are closely related to collateral diseases.By analyzing the pathological state of RA microangiogenesis,the physiological characteristics of collaterals and the pathological characteristics of collateral diseases,the paper discusses the disease and views collaterals as the locations where pathogens hide,develop,invade and block,deeming collateral diseases as the pathological basis of RA,collateral deficiency as its fundamental pathogenesis,and the invasion of collaterals by cold-dampness due to wind as the key to its pathogenesis.Based on the theories of collateral diseases and wind herbs,this paper aims to recognize the role of Duhuo Jisheng Decoction in the treatment of RA from the perspective of Duhuo Jisheng Decoction as a wind-treating agent,proposing that wind medicines be applied timely to treat collateral stagnation in the early stage of RA,to treat collateral stasis and obstruction so as to invigorate the spleen and resolve blood stasis in its middle stage,and to treat collateral deficiency by invigorating the kidney in its late stage.This paper discusses the combination principle of Duhuo Jisheng Decoction with wind herbs and other drugs in the different stages of RA,so as to enrich the compatibility theory of Duhuo Jisheng Decoction,expand the clinical guiding significance of Duhuo Jisheng Decoction,and provide a reference for its clinical application.

rheumatoid arthritisbi syndromeDuhuo Jisheng Decoctioncollateral diseasewind herbs

张楠、郑碧如、辛小红

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新疆医科大学中医学院,乌鲁木齐 830011

类风湿关节炎 痹病 独活寄生汤 络病 风药

国家自然科学基金项目

81760912

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(1)
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