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水蛭和黄连随证施量策略在糖尿病肾病治疗中的运用

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糖尿病肾病是主要的糖尿病微血管并发症之一,该疾病早中期,患者常没有明显的临床症状,但会有蛋白尿,ACR升高等异常指标,因此在准确辨证基础上,应用针对降蛋白尿和降糖的中药水蛭和黄连,往往能获得较好的疗效.对于此类药物的剂量,要结合随证施量策略,选定调整剂量的指征,找准变量的时机,控制好药物用量的范围,才能在确保用药安全的基础上取得最佳疗效.
Dose applying strategies of leech and golden thread according to syndromes in the treatment of diabetic kidney disease
Diabetic kidney disease(DKD)is one of the most important diabetic microvascular complications.In the early and middle stages of the disease,patients usually manifests no obvious clinical symptoms,only displaying some abnormal indicators such as proteinuria and elevated ACR.Therefore,on the basis of accurate syndrome differentiation,the application of hypoglycemic and proteinuria-lowering drugs,such as leech and golden thread,can often achieve better curative results.For the dose of the target drugs,it is necessary to implement the strategy of applying dose according to specific syndrome,selecting the indications for adjusting the dose,identifying the timing and controlling the dosage range,so as to achieve the best curative effect on the basis of ensuring medication safety.

diabetic kidney diseaseurinary albumin to creatinine ratioapplying dose according to syndromeleechgolden thread

高晴、姬航宇、连凤梅

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北京中医药大学,北京 100029

中国中医科学院广安门医院,北京 100053

糖尿病肾病 尿微量白蛋白肌酐比值 随证施量 水蛭 黄连

国家自然科学基金国家重点基础研究发展计划(973计划)

812740002010CB530601

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(1)
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