Clinical efficacy of Juanyu Anshen Formula in the treatment of insomnia combined with depression disorder with the syndrome of liver depression and qi stagnation
Objective To observe the clinical efficacy of Juanyu Anshen Formula in treating insomnia with depression disorder with the syndrome of liver depression and qi stagnation.Methods Sixty insomnia patients accompanied by depression disorder with the syndrome of liver depression and qi stagnation were collected from the First Affiliated Hospital of Changchun University of Chinese Medicine.They were randomly divided into an observation group and a control group,with 30 cases in each group.The control group was treated with oral administration of eszopiclone,while the observation group was treated with modified Juanyu Anshen Formula.Both groups were treated for 15 days as one course of treatment,with a total of 2 courses of treatment.Before and after treatment between two groups,the Pittsburgh Sleep Quality Index(PSQI)was used to evaluate their sleep status,and the Hamilton Depression Scale(HAMD)was used to observe their depression condition,and their TCM symptom scores were used to evaluate their clinical symptoms.Results After treatment,the total clinical effective rate in the observation group(90.0%,27/30)was higher than that of the control group(63.3%,19/30),and the total PSQI score,total HAMD score,and TCM syndrome score in the observation group were significantly lower than those in the control group(P<0.05).Conclusion The Juanyu Anshen Formula has a good clinical efficacy in treating insomnia with depression with the syndrome of liver stagnation and qi stagnation,and its clinical efficacy and mechanisms of action need be further explored.
liver depression and qi stagnationJuanyu Anshen Formulaclinical efficacyinsomniadepression
万方数据
维普
