吉林中医药2024,Vol.44Issue(3) :307-310.DOI:10.13463/j.cnki.jlzyy.2024.03.015

小青龙加石膏汤治疗痰热蕴肺型支气管扩张症

Effect of Xiaoqinglong plus Shigao Decoction in the treatment of bronchiectasis with the syndrome of phlegm-heat amassing in lungs

史澍 王骐 赵宁
吉林中医药2024,Vol.44Issue(3) :307-310.DOI:10.13463/j.cnki.jlzyy.2024.03.015

小青龙加石膏汤治疗痰热蕴肺型支气管扩张症

Effect of Xiaoqinglong plus Shigao Decoction in the treatment of bronchiectasis with the syndrome of phlegm-heat amassing in lungs

史澍 1王骐 1赵宁1
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作者信息

  • 1. 北京中医药大学附属护国寺中医医院针灸科,北京 100035
  • 折叠

摘要

目的 探讨小青龙加石膏汤治疗痰热蕴肺型支气管扩张症的效果.方法 选择2021年5月-2023年3月收治的112例痰热蕴肺型支气管扩张症患者为研究对象,采用随机数表法分为观察组与对照组,各56例.对照组采用常规西医治疗,观察组采用小青龙加石膏汤联合常规西医治疗,比较2组中医证候积分、治疗效果、炎症指标、呼吸功能、不良反应发生情况.结果 治疗后,观察组中医证候积分低于对照组(P<0.05);观察组FEV1、FVC、PEF、FEV1/FVC水平高于对照组(P<0.05);观察组CRP、PCT、IL-1β水平低于对照组(P<0.05);观察组总有效率(91.07%,51/56)高于对照组(71.43%,40/56)(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05).结论 小青龙加石膏汤联合常规西医治疗能够有效改善痰热蕴肺型支气管扩张症患者的炎症指标及呼吸功能,降低中医证候积分,提高治疗效果,值得推广.

Abstract

Objective To observe the effect of Xiaoqinglong plus Shigao Decoction in the treatment of bronchiectasis with the syndrome of phlegm-heat amassing in lungs.Methods A total of 112 bronchiectasis patients with the syndrome of phlegm-heat amassing in lungs treated in our hospital from May 2021 to March 2023 were selected as the study subjects,and were divided into an observation group and a control group using a random number table method,with 56 cases in each group.The control group received a conventional western medicine treatment,while the observation group was treated with Xiaoqinglong plus Shigao Decoction combined with the western medicine treatment.The TCM syndrome scores,therapeutic effect,inflammation indexes,respiratory function and occurrence of adverse reactions were compared between the two groups.Results After treatment,the TCM syndrome scores were lower in the observation group than those in the control group(P<0.05).The levels of FEV1,FVC,PEF,and FEV1/FVC were higher in the observation group than those in the control group(P<0.05).The levels of CRP,PCT and IL-1β were lower in the observation group than those in the control group(P<0.05).The total effective rate of the observation group(91.07%,51/56)was higher than that of the control group(71.43%,40/56)(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Xiaoqinglong plus Shigao Decoction combined with the conventional western medicine treatment can effectively improve the inflammation indexes and respiratory function of bronchiectasis patients with the syndrome of phlegm-heat amassing in lungs,reduce their TCM syndrome scores,and improve therapeutic effect,which is worthy of promotion.

关键词

小青龙加石膏汤/支气管扩张症/治疗效果/炎症指标/呼吸功能/不良反应

Key words

Xiaoqinglong plus Shigao Decoction/bronchiectasis/therapeutic effect/indicator of inflammation/respiratory function/adverse reaction

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基金项目

北京市科技计划项目(Z201100000516007)

出版年

2024
吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
参考文献量20
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