Research progress of the mechanisms of acupuncture treatment of polycystic ovary syndrome with insulin resistance
Polycystic ovary syndrome(PCOS)is the most prevalent endocrine disease in women of childbearing age.Insulin resistance(IR)is the main pathological basis for the development of PCOS,and 50%to 70%of patients with PCOS are manifested by IR.Modern medicine lacks an effective,safe and targeted treatment for PCOS-IR,yet acupuncture,as an effective means in this respect,is increasingly widely used in clinical practice.At present,the mechanisms of acupuncture on the treatment of the disease have not been fully clarified,so this article summarizes the research literature on the acupuncture treatment of PCOS-IR in recent years,which mainly focuses on the mechanisms of abnormalities in the PI3K/AKT signaling pathway,levels of inflammatory factors,abnormal expression of adipokines,and levels of Kisspeptin,β-endorphin secretion and release,expecting to provide new ideas and treatment methods for modern clinical treatment of this disease.
polycystic ovarian sydromeinsulin resistanceacupuncturemechanism research
万方数据
维普
