Effects of Huayu Jiegu Decoction with calcium carbonate D3 tablets on the bone metabolism and bone healing indexes in patients with osteoporotic thoracolumbar fracture after surgery
Objective To investigate the effects of Huayu Jiegu Decoction on the bone metabolism and bone healing indexes in patients with osteoporotic thoracolumbar fracture after surgery.Methods A total of 100 patients with osteoporotic thoracolumbar fracture admitted to our hospital from September 2020 to December 2022 were selected and divided into an observation group(treated with calcium carbonate D3 tablets plus modified Huayu Jiegu Decoction,50 cases)and a control group(treated with calcium carbonate D3 tablets,50 cases)according to the random number table method.The therapeutic effects of the two groups were compared,and the scores of traditional Chinese medicine symptoms including back pain,flaccidity,weakness,dark red tongue,and inability to carry weight were compared between the two groups before and after treatment.The bone density levels of femoral neck,lumbar spine and intertrochanteric bone were compared between the two groups before and after treatment.The levels of osteoprotegerin(OPG),alkaline phosphatase(ALP)and osteocalcin(BGP)were compared between the two groups before and after treatment,and the effect of fracture healing was compared between the two groups.Results The total effective rate in the observation group(92.00％)was significantly higher than that in the control group(70.00％)(P＜0.05).After treatment with Huayu Jiegu Decoction,the scores of back pain,flaccidity,weakness,dark red tongue,inability to carry weight were lower in the observation group than those in the control group(P＜0.05).After treatment with Huayu Jiegu Decoction,the bone density levels of femoral neck,lumbar spine and intertrochanteric bone in the observation group were higher than those in the control group(P＜0.05).The OPG,ALP and BGP levels were higher in the observation group than those in the control group after treatment with Huayu Jiegu Decoction(P＜0.05).Compared with the control group,the fracture healing effects of grade Ⅰ and Ⅱ in the observation group were lower,while the fracture healing effects of grade Ⅲ and Ⅳ were higher(P＜0.05).Conclusion Huayu Jiegu Decoction can effectively relieve the clinical symptoms of patients with osteoporotic fracture after operation,improve the levels of bone density,improve bone metabolism,promote bone healing,worthy of clinical promotion.
万方数据
维普
