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补肾健脾化瘀方治疗肾虚血瘀型崩漏

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目的 探究补肾健脾化瘀方治疗肾虚血瘀型崩漏的临床疗效及对子宫内膜容受性的影响.方法 选取2020年3月-2023年1月常州市武进中医医院收治的崩漏患者82例,随机分为观察组与对照组,各41例,对照组予人工孕激素治疗,观察组在对照组基础上联合补肾健脾化瘀方治疗.维持治疗3个月经周期后,比较2组中医证候积分、临床疗效、子宫内膜厚度、血流阻力指数(RI)、孕酮(P)、雌二醇(E2)、黄体生成素(LH)、月经量、出血时间、血红蛋白水平变化情况及不良反应发生率.结果 观察组总有效率(100.00%,41/41)高于对照组(87.8%,36/41)(P<0.05);与治疗前比较,治疗后2组主症、次症评分均降低,观察组优于对照组(P<0.05);2组RI指数均降低,观察组优于对照组(P<0.05);2组子宫内膜厚度均增高,观察组高于对照组(P<0.05);2组P、E2、LH水平均升高,观察组高于对照组(P<0.05);2组月经量、出血时间均降低,血红蛋白水平升高,且观察组优于对照组(P<0.05).2组治疗期间均无不良反应发生.结论 补肾健脾化瘀方治疗肾虚血瘀型崩漏,可调节性激素水平,改善子宫内膜容受性,缓解症状,提高临床疗效,安全性良好.
Analysis of the therapeutic effect of tonifying the kidney,strengthening the spleen,and resolving blood stasis formula on kidney deficiency and blood stasis type metrorrhagia and leakage
Objective To explore the effect of bushen jianpi huayu recipe on treating metrorrhagia and metrorrhagia of kidney deficiency and blood stasis type and its impact on endometrium.Methods A total of 82 patients with metrorrhagia and metrorrhagia admitted to Wujin Hospital of Traditional Chinese Medicine in Changzhou City from March 2020 to January 2023 were selected.They were randomly divided into an observation group and a control group with 41 cases each.The control group was treated with artificial progesterone,and the observation group was treated on the basis of the control group with the bushen jianpi huayu recipe.After 3 menstrual cycles of maintenance treatment,the TCM syndrome scores,therapeutic effects,endometrial thickness,blood flow resistance index(RI),progesterone(P),estradiol(E2),luteinizing hormone(LH),menstrual volume,bleeding time,hemoglobin level,and adverse reactions of the two groups of patients were compared.Results After treatment,the main and secondary syndrome scores in both groups decreased,and the observation group was lower than the control group(P<0.05).The total effective rate(100%)in the observation group was higher than that in the control group(87.8%)(P<0.05).After treatment,the RI index of both groups decreased,and the observation group was lower than the control group(P<0.05);The endometrial thickness of both groups increased,and the observation group was higher than the control group(P<0.05).After treatment,the levels of P,E2,and LH in both groups increased,and the observation group was higher than the control group(P<0.05).After treatment,the menstrual volume and bleeding time of both groups of patients decreased,while hemoglobin levels increased;The menstrual volume and bleeding time of the observation group patients were lower than those of the control group,and the hemoglobin level was higher than that of the control group(P<0.05).No adverse reactions occurred during treatment in both groups.Conclusion Bushen jianpi huayu recipe for treating metrorrhagia and metrorrhagia due to kidney deficiency and blood stasis can help improve clinical efficacy,regulate sexual hormone levels and menstrual symptoms,improve endometrial receptivity,and have good safety.

collapse and leakagekidney deficiency and blood stasistonifying the kidneystrengthening the spleenremoving blood stasisendometrium

杨泽曙、上官立琴

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常州市武进中医医院妇科,江苏 常州 213161

崩漏 肾虚血瘀 补肾 健脾 化瘀 子宫内膜

江苏省中医药科技计划项目

LHGJ20210023

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(4)
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