首页|经典名方百合地黄汤的历史衍变及研究进展

经典名方百合地黄汤的历史衍变及研究进展

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百合地黄汤是《古代经典名方目录(第一批)》中收录方剂.通过整理古代医籍、现代文献,系统考证百合地黄汤处方来源、组方、主治等历史沿革及研究现状,发现该方最早见于汉代名医张仲景所著《金匮要略》,组方"少而精",主治百合病,后世医籍记载主治与原方基本一致.处方剂量、药味炮制及煎服法均沿袭原方,鲜有改动.现代药理研究发现其具有抗抑郁、失眠、抗肿瘤等作用,主要用该经典名方治疗神经精神系统疾病,如抑郁症、焦虑症、睡眠障碍、心理亚健康状态等.通过全面文献考证,可为经典名方百合地黄汤的现代开发提供理论依据与文献参考.
Historical evolution and research progress of the classical prescription of Baihe Dihuang decoction
Baihe Dihuang decoction is listed in the Catalogue ofAncient Famous Classical Prescriptions(First Batch).This paper systematically researches the historical evolution and research status of the origin,composition and indications of this formula by sorting out ancient medical books and modern literature.It is found that Baihe Dihuang decoction was first recorded in Jingui Yaolue(Synopsis of Golden Chamber)written by Zhang Zhongjing,a famous doctor in the Han dynasty.The prescription,with fewer yet refined herbs,is mainly used to treat lily diseases,with which the indications recorded in the later medical books are basically consistent.Besides,the prescription dosage,the processing of medicinal herbs,and the method of decocting and taking all follow the original formula,with few modifications.Modern pharmacological studies have found that it has antidepressant,anti-insomnia,anti-tumor,and other effects,mainly used to treat neuropsychiatric diseases such as depression,anxiety,sleep disorders,and mental sub-health states.In short,this paper can provide a theoretical basis and literature reference for the modern development of this famous classical formula.

Baihe Dihuang decoctionclassical prescriptionhistory evolutionpharmacological actionclinical application

许俊洁、刘佳、徐娇雅、郑新春

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上海中医药大学附属光华医院关节内科,上海 200050

百合地黄汤 经典名方 历史沿革 药理作用 临床应用

2021年度上海中医药大学预算内项目上海市科委医学创新研究专项科技计划项目上海市卫生健康委员会科研课题计划项目上海中医药大学预算内项目

2021WK11721Y119220020204Y03972021LK011

2024

10.13463/j.cnki.jlzyy.2024.04.024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子：0.843
ISSN：1003-5699
年,卷(期)：2024.44(4)
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