首页|从"肾虚痰瘀"论治脑白质变性

从"肾虚痰瘀"论治脑白质变性

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脑白质变性(white matter lesions,WML)是常见的脑小血管病,以信息处理速度下降、行动迟缓和大小便异常为主要临床表现,临床发展为痴呆的可能性大.从"肾虚痰瘀"探析脑白质变性的机制与治疗,病性本虚标实,肾虚为本,髓海失养,精血化生不足,脑不得充,"技巧"不出;痰瘀阻络为标,多由肾虚气血化生不足,推动无力,痰瘀互结,闭阻脉络,脉络失养,形衰神减.临床治疗应紧抓该病的病机要点,培补肾精固其本,化痰通络祛其标,可提高临床疗效.
Differentiating and treating cerebral white matter lesions from the perspective of kidney deficiency and phlegm stasis
Cerebral white matter lesions(WML),a common type of cerebral small vessel disease,is in clinic primarily manifested as decreased information processing speed,slow motor function,and urination and defecation abnormalities,which has a significant potential for clinical progression to dementia,causing a considerable inconvenience to patients,their families,and the society.This article examines the mechanisms and treatment of cerebral white matter lesions from the perspective of"kidney deficiency and phlegm stasis",concluding that it is of nature of deficiency in its root cause and excess in its manifestations,among which kidney deficiency acts as its root cause,inducing the malnutrition of marrow sea,the inadequate transformation of essence and blood,leading to insufficient cerebral nourishment and impaired cognitive function.On the other hand,phlegm stasis blocking collaterals is perceived as its manifestation,which mostly arises from deficient kidney essence and insufficient qi and blood transformation,leading to a weak propulsion,intermingled phlegm and blood stasis,obstructing vessels and meridians,resulting in a malnutrition in them and a decline in a person's physical and mental aspects.The clinical treatment of the disease should underscore its key pathogenesis,cultivating and reinforcing kidney essence to consolidate body resistance,resolving phlegm and unblocking collaterals to eliminate its manifestations,improving its clinical efficacy.

kidney deficiencyphlegm and blood stasiscerebral white matter lesions

胡天时、马培、龚洲、付宏宇、贾岳津、刘鑫雨、吴柔燕、刘金瑛、李志更、岳利峰

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北京中医药大学东直门医院,北京 100700

中国医学科学院药用植物研究所,北京 100193

中国中医科学院中医基础理论研究所,北京 100700

肾虚 痰瘀 脑白质变性

国家自然科学基金面上项目中国医科院医学与健康科技创新工程项目

821740462021-I2M-1-031

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(5)
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