首页|基于肠道菌群论健脾通腑法治疗桥本甲状腺炎

基于肠道菌群论健脾通腑法治疗桥本甲状腺炎

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桥本甲状腺炎(HT)是临床常见自身免疫性疾病,改善肠道菌群是桥本甲状腺炎治疗的研究热点.脾虚是桥本甲状腺炎的核心病机,健脾通腑治疗桥本甲状腺炎疗效良好.脾脏与肠道菌群在生理病理方面关系密切,健脾通腑和改善肠道菌群作用机制具有一定相关性.健脾通腑类药物可促进胃肠道蠕动、改善免疫指标、恢复免疫细胞平衡等,重塑肠道微环境的免疫平衡,推测改善肠道菌群可能是健脾通腑法治疗桥本甲状腺炎的作用机制之一.
Treatment of Hashimoto thyroiditis by invigorating the spleen and dredging the fu viscera based on the theory of improving intestinal flora
Hashimoto thyroiditis(HT)is a common autoimmune disease in clinic,and improving intestinal flora is a research hotspot in its treatment.Spleen deficiency is the core pathogenesis of HT,hence strengthening the spleen and clearing the fu viscera is an effective method for treating the disease.The spleen and intestinal flora are closely related in their physiological and pathological aspects,and there is a certain correlation between strengthening the spleen and dredging the fu organs and improving the functions of intestinal flora.The drugs for invigorating the spleen and dredging the fu organs can reshape the immune balance of the intestinal microenvironment by promoting gastrointestinal peristalsis,improving immune indicators,restoring the immune cell balance,etc.It is speculated that improving intestinal flora may be one of the mechanisms of invigorating the spleen and dredging the fu viscera in treating Hashimoto thyroiditis.

Hashimoto thyroiditisintestinal floramethod for strengthening the spleen and dredging the fu viscera

李欣怡、祁烁、袁姣姣、耿文倩、吴艳珂、司新颖、马文源、丁治国

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北京中医药大学东直门医院,北京 100700

北京中医药大学孙思邈医院,陕西 铜川 727031

桥本甲状腺炎 肠道菌群 健脾通腑法

陕西省中医药局科研项目陕西省秦创原"科学家+工程师"队伍建设项目

2021-GJ-LC0022022KXJ-019

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(5)
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