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重构本草——巴戟天

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通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出巴戟天功效主要为:补肾阳,强筋骨,祛风湿.症靶为阳痿、月经不调、哮喘.标靶为少精死精.现代药理发现巴戟天及其有效成分具有抗氧化、延缓衰老、免疫调节、抗疲劳、抗骨质疏松、平喘、改善生殖功能、抗炎、调血糖、降压、心脑血管保护等作用.本品无毒,但阴虚火旺有热者,不宜使用.临床常用剂量为10~20g.当根据不同疾病,或同一疾病的不同阶段进行辨证使用,并积极探索巴戟天用量与症靶、标靶的量效关系构建.
Reconstruction of Chinese materia medica-morinda root
Through the investigation of ancient books and literature,the combing of modern research results of traditional Chinese medicine,combined with the knowledge and application experience of well-known experts and scholars in the fields of clinical medicine and Chinese pharmacy,it is concluded that morinda root mainly has the following characteristics:Its effects mainly involve tonifying kidney yang,strengthening muscles and bones,and dispelling wind and dampness.The symptom targets of the herb include impotence,menstrual disorders,asthma,while its biological indicator targets are oligospermia and necrospermia.Modern pharmacology has found that morinda root and its active ingredients have the effects of anti-oxidation,anti-aging,immune regulation,anti-fatigue,anti-osteoporosis,relieving asthma,improving reproduction,anti-inflammation,regulating blood glucose,reducing blood pressure,cardiovascular and cerebrovascular protection,etc.This product is non-toxic,but should not be used for those with the syndromes of yin deficiency,fire effulgence,and excessive heat.Its routine clinical dosage range is 10-20 g,which should be determined according to different diseases or different stages of the same disease,and the dose-effect relationship between their dosage and their symptom targets or biochemical indicator targets should be actively explored and constructed.

morinda rootsymptom targetbiochemical indicator targetreconstruction of Chinese materia medicaclinical verification

孙文杰、孙玉婷、安学冬、姬航宇、连凤梅

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中国中医科学院广安门医院,北京 100053

巴戟天 症靶 标靶 重构本草 临床回归

中华中医药学会2023-2025年度青年人才托举工程项目

2023-QNRC2-A05

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(6)