摘要
代谢相关脂肪性肝病(metabolic associated fatty liver disease,MAFLD)是指肝脏脂肪代谢功能障碍引起脂肪过度堆积的代谢性疾病.杨震认为代谢相关脂肪性肝病病因多为饮食失当、劳逸失和、忧思恼怒、情志失调、久病体虚等所致;主要为郁、热、湿、瘀、痰等因素损伤肝脾,使湿、热、瘀、痰结于肝络而发病,病位在肝,涉及脾、胃、肾等脏腑.杨震基于"相火理论",应用郁热相火、湿热相火、瘀热相火理论治疗代谢相关脂肪性肝病,疗效显著,附医案一则以佐证.
Abstract
Metabolic associated fatty liver disease(MAFLD)refers to a metabolic disease in which liver fat metabolism dysfunction leads to excessive accumulation of fat.Yang Zhen believes that the causes of MAFLD mostly involve improper diet,imbalance of work and rest,worry and anger,emotional disorders,and physical weakness due to a prolonged illness,etc.,with its pathogenesis mainly featuring factors such as depression,heat,dampness,blood stasis,and phlegm causing damages to the liver and spleen,so that dampness,heat,stasis,and phlegm accumulate in the liver meridians and induce the disease.The disease is located in the liver and involves zang-fu viscera such as the spleen,stomach,and kidneys.Based on the theory of"ministerial fire",Yang Zhen applies the theories of stagnated heat ministerial fire,damp-heat ministerial fire,blood stasis-heat ministerial fire in the treatment of MAFLD,achieving significant therapeutic effects.A medical case is attached as evidence in this paper.
基金项目
国家中医药管理局第四届国医大师传承工作室和第二届全国名中医传承工作室建设项目(国中医药办人教函[2022]245号)
陕西省中医药管理局科技产业处项目(SZY-KJCYC-2021-GJ-LC005)
西安市创新能力强基计划-医学研究项目(21YXYJ0059)