The effect of Xiaozhong Shengji Tang on anorectal dynamics in postoperative patients with anal fistula
Objective To explore the effect of Xiaozhong Shengji Tang on inflammatory factors in wound exudates and the changes in anorectal dynamics in patients after anal fistula surgery.Methods A total of 62 postoperative patients with anal fistula admitted to the Henan Provincial Hospital of Traditional Chinese Medicine from October 2022 to September 2023 were selected as the research subjects and divided into a control group and an observation group with the random number table method,with 31 cases in each group.The control group received a routine treatment after anal fistula surgery,while the observation group received a fumigation and washing treatment with Xiaozhong Shengji Tang.Both groups were treated for 7 days and were followed up for 3 weeks.The clinical efficacy after treatment,the wound healing,anorectal dynamics,inflammatory factors in wound exudates,tissue growth,and wound healing related factors before and after treatment were compared between the two groups.Results After 7 days of treatment,the total effective rate of the observation group was 96.77％,higher than 74.19％in the control group(P＜0.05).After treatment,the time for the shedding of carrion,disappearance of rectal bleeding,wound healing,and wound exudation was shorter in the observation group than that in the control group,while the wound healing rate was higher than that in the control group(P＜0.05).Compared with before treatment,after 7 days of treatment,the longest contraction time of anal canal in both groups was prolonged,and it was longer in the observation group than that in the control group.The levels of anal canal resting pressure,rectal resting pressure,interleukin-6(IL-6),C-reactive protein(CRP),tumor necrosis factor-α(TNF-α),interferon-γ(IFN-γ)in wound exudates were all decreased,and compared with the control group,the observation group was much lower.The levels of anal canal systolic pressure,interleukin-10(IL-10)in wound exudates,and the levels of factors related to tissue growth and wound healing were all increased,and compared with the control group,the observation group was much higher(P＜0.05).Conclusion In the treatment of postoperative patients with anal fistula,Xiaozhong Shengji Tang can effectively regulate the levels of tissue growth and wound healing related factors,promote wound healing,improve anorectal motility,effectively reduce inflammatory reactions,and promote clinical efficacy.
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