吉林中医药2024,Vol.44Issue(12) :1392-1395.DOI:10.13463/j.cnki.jlzyy.2024.12.003

基于"肺与大肠相表里"理论探讨细胞焦亡在重症急性胰腺炎肺损伤的作用

Exploring the role of pyroptosis in severe acute pancreatitis-associated lung injury based on the theory of"lung and large intestine forming an exterior-interior relationship"

安晓霞 李慧 王振刚 娄余 陈国忠
吉林中医药2024,Vol.44Issue(12) :1392-1395.DOI:10.13463/j.cnki.jlzyy.2024.12.003

基于"肺与大肠相表里"理论探讨细胞焦亡在重症急性胰腺炎肺损伤的作用

Exploring the role of pyroptosis in severe acute pancreatitis-associated lung injury based on the theory of"lung and large intestine forming an exterior-interior relationship"

安晓霞 1李慧 2王振刚 3娄余 3陈国忠3
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作者信息

  • 1. 广西中医药大学,南宁 530001;广西中医药大学第一附属医院,南宁 530023
  • 2. 广西中医药大学,南宁 530001
  • 3. 广西中医药大学第一附属医院,南宁 530023
  • 折叠

摘要

细胞焦亡是一种程序性死亡,调控炎症因子表达,介导炎症反应.重症急性胰腺炎是炎症性疾病,其中相关性肺损伤是常见且首发并发症."肺与大肠相表里"结合现代研究"肠道菌群""胰-肠-肺轴"探讨其病理过程,将"湿热毒瘀"病因病机与细胞焦亡的微观联系相结合探究中西医结合治疗的新靶点.

Abstract

Pyroptosis is a kind of programmed cell death,which regulates the expression of inflammatory factors and mediates inflammatory reactions.Severe acute pancreatitis is an inflammatory disease,with lung injury as its common and initial complication.Based on the theory of"the lung and the large intestine forming an exterior-interior relationship",combined with modern research on"intestinal flora"and"pancreas-intestine-lung axis",this paper explores the pathological process of severe acute pancreatitis-associated lung injury,approaching a new target of integrated traditional Chinese and western medicine from the micro-relationship between its pathogenesis of"dampness,heat,toxins,blood stasis"and pyroptosis.

关键词

重症急性胰腺炎肺损伤/细胞焦亡/肠病及肺/湿热毒瘀

Key words

severe acute pancreatitis-associated lung injury/pyroptosis/intestine disease causing pulmonary disease/dampness,heat,toxins,blood stasis

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出版年

2024
吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
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