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重构本草——蜈蚣

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通过古籍文献调研、中医药现代研究成果的梳理,结合中医临床及中药学等学科领域内知名专家学者的认识及应用经验,归纳出蜈蚣:功效主要为息风止痉,通络止痛,攻毒散结;症靶为关节疼痛、痉挛抽搐、疮疡、阳痿等;现代药理研究发现蜈蚣及其有效成分具有镇痛、调节免疫、抗炎、抗惊厥、促进皮损恢复等作用;蜈蚣有一定的毒性,应用时需严格把握好用量,亦需尽量避免长期使用;临床使用剂量为1.5~15 g,打粉冲服常用量为1.5~3 g,内服时当辨病辨证使用,并积极探索蜈蚣用量与症靶的量效关系构建.
Reconstruction of Chinese materia medica--centipede
Through investigating ancient books,combing the modern research results of traditional Chinese medicine,combined with the understandings and application experience of well-known experts and scholars in the fields of clinical traditional Chinese medicine and Chinese materia medica,it is concluded that centipede mainly has the following characteristics:Its effects mainly involve relieving spasm by calming endogenous wind,dredging channels to relieve pain,counteracting toxic substances and resolving hard masses.Its symptom targets feature joint pain,twitch and spasm,sores and ulcers,and impotence.Modern pharmacology finds that centipede and its active ingredients have pain-relieving,immune regulating,anti-inflammatory,anticonvulsive,and promoting skin recovery effects.It has certain toxicity,thus should be taken with caution and not be used for a long term.Its clinical dosage is 1.5-15 g.The usual dosage of its powder is 1.5-3g.When taken orally,it should be used according to the syndrome differentiation of different diseases or of the same disease at different stages,and the dose-effect relationship between its dosage and its symptom targets should be actively explored.

centipedesymptom targetsjoint paintwitch and spasmsore and ulcerimpotenceclinical verification

林潼、张琪棋、康梦娇、张伟、赵林华

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中国中医科学院广安门医院代谢病研究所,北京 100053

浙江中医药大学第一临床医学院,杭州 310053

甘肃中医药大学基础医学院,兰州 730000

蜈蚣 症靶 关节疼痛 痉挛抽搐 疮疡 阳痿 临床回归

2024

吉林中医药
长春中医药大学

吉林中医药

CSTPCD
影响因子:0.843
ISSN:1003-5699
年,卷(期):2024.44(12)