首页|多酸基金属—有机复合物的合成和对H2O2的检测

多酸基金属—有机复合物的合成和对H2O2的检测

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设计合成多酸基金属-有机晶态复合物,研究其对于过氧化氢小分子的催化活性,为开发新型生物小分子传感器提供新途径.利用水热法合成和X-射线单晶衍射表征多酸基金属有机晶态复合物;利用紫外-可见分光光度研究其对过氧化氢小分子的催化活性.成功制备并解析出多酸基金属有机晶态复合物,其分子式为H4[Cu2(bim)4][SiW12O40]2·8H2O,拟酶活性研究表明复合物具有过氧化酶活性,其最优催化条件为:pH=3,40℃,反应时间为4min,对过氧化氢的检测区间为1~100 μmol× L-1,检测限为0.18 μmolL-1.多酸基金属-有机晶态复合物尽管对于生物小分子传感表现出优异的检测性能,但是其种类和结构对其催化活性是有一定的影响,其构效关系还需要进一步深入研究.
Synthesis and H2O2 Detection of POMs Based Metal-organic Framework Compounds
Objective:To design and synthesize POMs based metal-organic crystalline com-pounds,and study their catalytic activity for H2O2,and provide a new approach for the development of new biological small molecule sensors.Method:Hydrothermal synthesis and X-ray single crystal dif-fraction were used to characterize POMs based metal-organic crystalline complexes.And UV-visible spectrophotometry was employed to study the catalytic activity of POMs based metal-organic crystal-line compounds to H2O2.Result:POMs based metal-organic crystalline compound was successfully prepared,and X-ray single diffraction analysis shows that the molecular formula is H4[Cu2(bim)4][SiW12O40]2·8H2O.Studies on enzymatic activity shows that the compound possesses peroxidase-like activity,and the optimal catalytic conditions are pH=3,40 ℃,reaction time of 4 minutes,and the de-tection range for H2O2 is 1~100 µmolL-1 with the detection limit of 0.18 μmolL-1.Conclusion:POMs based metal-organic crystalline compounds exhibit excellent detection performance for biological small molecule sensing,but their types and structures have a certain impact on their catalytic activity,and their structure-activity relationship still needs further in-depth research.

POMsmetal-organic frameworknanozymeH2O2

蔡运蘅、庞启洋、魏玉普、高景奎、沙靖全

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济宁学院化学化工与材料学院,山东曲阜 273155

多酸 金属-有机框架 纳米酶 过氧化氢

2022年济宁学院大学生研究性学习与创新性实验计划项目暨国家级、省级创新创业训练计划项目

S202210454001

2024

佳木斯大学学报(自然科学版)
佳木斯大学

佳木斯大学学报(自然科学版)

影响因子:0.159
ISSN:1008-1402
年,卷(期):2024.42(2)
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