Clinical efficacy of robot-assisted radical prostatectomy for large-volume localized prostate cancer(with surgical video)
Objective:To analyze the clinical efficacy of robot-assisted radical prostatectomy(RARP)for large-volume localized prostate cancer(PCa).Methods:118 patients with large-volume localized PCa who were treated in Shaanxi Provincial People's Hospital from June 2020 to June 2023 were selected.They were randomly divided into the control group(n=59)and the study group(n=59)using a random number table.The control group received conventional laparoscopic radical prostatectomy(LRP),while the study group received RARP.The urinary incontinence,sexual function,serum prostate-specific antigen(PSA),free prostate-specific antigen(f-PSA),complication rate and positive margins of patients in the two groups were compared.Results:The international consultation on incontinence questionnaire short form(ICIQ-SF)scores,serum PSA and f-PSA levels of patients in the two groups were both lowered after 6 months of treatment,and they were lower in the study group than the control group after treatment.The International Index of Erectile Function 5(IIEF-5)scores were lowered in both groups after 6 months of treatment comparing with that before treatment,and the IIEF-5 scores were higher in the study group than the control group after treatment.There was no statistically significant difference in the complication rate and positive margin rate between the two groups.Conclusion:Patients with large-volume localized PCa undergoing RARP can improve urinary incontinence and sexual function,lower serum PSA and f-PSA levels without increasing the complication rate and positive margin rate.
Prostate CancerRadical ProstatectomyLarge-volume Prostate VolumeRobot-assisted SurgeryOncological ResultSexual Function
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