The rat eustachian tube:Anatomical,histological,and radiological features

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外文摘要：Purpose:This study investigated the anatomical and histological characteristics of the rat Eustachian tube(E-tube)and the feasibility of Eustachian tubography in a rat model.Materials and methods:Fifteen male Wistar rats were used in this study,and the bilateral E-tubes of each rat were examined.Ten E-tubes were used for anatomical studies,another ten for histological analysis,and the other ten for Eustachian tubography.Five rats were euthanized and decapitated,and ten E-tubes were dissected to describe the anatomy of the E-tube.Ten E-tube specimens obtained from five other rats were sectioned to investigate E-tube histology.Eustachian tubography was performed on the bilateral E-tubes of the other five rats using the trans-tympanic approach.Results:The rat E-tubes consisted of bony and membranous parts.Cartilage and bone tissue covered only the bony part.The E-tubes'mean diameter and overall length were 2.97 mm and 4.96 mm,respectively.The tympanic orifices'mean diameter was 1.21 mm.The epithelium of E-tubes was mainly composed of pseudostratified cili-ated and goblet cells.Eustachian tubography was successfully performed on both sides of the E-tube for each rat.The technical success rate was 100％,the average running time was 4.9 min,and no procedure-related compli-cations occurred.On tubography images,the E-tube,tympanic cavity,and nasopharynx could be identified because of the visualization of bony landmarks.Conclusion:In this study,we described the anatomical and histological features of rat E-tubes.With the aid of these findings,E-tube angiography was successfully performed using a transtympanic approach.These results will facilitate further investigation of E-tube dysfunction.

外文关键词：

RatsEustachian tubeAnatomyHistologyRadiography

作者：

Zhe Wang、Hong-Tao Hu、Nader Bakheet、Sung Hwan Yoon、Jung-Hoon Park、Kun Yung Kim、Jae Yong Jeon、Woo Seok Kang、Ye Ree Kim、Jorge E.Lopera、Hong Ju Park、Ho-Young Song

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作者单位：

Department of Radiology and Research Institute of Radiology,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea

Department of Radiology,Tianjin Medical University General Hospital,Anshan Road 154,Heping District,CN,300052,China

Department of Minimal-Invasive Intervention,Affiliated Cancer Hospital of Zhengzhou University,127 Dongming Road,Zhengzhou City,Henan Province,450003,China

Gastrointestinal Endoscopy and Liver Unit,Kasr Al-Ainy Faculty of Medicine,Cairo University,Cairo,Egypt

Biomedical Engineering Research Center,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea

Department of Radiology,Biomedical Research Institute of Chonbuk National University Hospital,Jeonju-si,Jeollabuk-do,Republic of Korea

Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital,Jeonju-si,Jeollabuk-do,Republic of Korea

Department of Rehabilitation Medicine,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea

Department of Otorhinolaryngology Head & Neck Surgery,Asan Medical Center,University of Ulsan College of Medicine,388-1,Poongnap 2-dong,Songpa-gu,Seoul,05505,Republic of Korea

Department of Radiology,UT Health Science Center at San Antonio,7703 Floyd Curl Drive,San Antonio,TX,78229,USA

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基金：

Korea Health Technology R&D Project,Ministry for Health,Welfare and Family Affairs,Republic of Korea

项目编号：

HI17C0881

出版年：

2023

DOI：

10.1016/j.jimed.2022.12.002

介入医学杂志(英文)

ISSN：

年,卷(期)：2023.6(1)

参考文献量37