首页|The effects of irreversible electroporation triggering anti-tumor immunity and the value of its combination with immunotherapy

The effects of irreversible electroporation triggering anti-tumor immunity and the value of its combination with immunotherapy

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Recently,interventional ablation techniques have gained prominence in tumor treatment guidelines and complement traditional approaches,such as surgery,chemotherapy,and radiotherapy.Conventional ablation techniques,such as microwave,radiofrequency,and cryoablation,have been used;however,they have certain limitations,including the risk of damaging surrounding normal tissues and the heat sink effect caused by tumor blood flow.1 Irreversible electroporation(IRE),an ablation technology independent of thermal energy,is a promising alternative.2 Clinical studies have demonstrated IRE's efficacy in treating tumors,such as pancreatic and liver tumors.3 Recent research has shown that IRE can elicit specific anti-tumor immune responses in the body.5 IRE also plays a crucial role in eliminating residual tumor cells postoperatively and preventing tumor recurrence.

Hengyu Li、Yu Zhou、Xiaoxia Guo、Qiwei Zhang、Xiaoyi Ding

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Department of Interventional Radiology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,No.197,Ruijin Er Road,Shanghai,200025,China

2023

介入医学杂志(英文)

介入医学杂志(英文)

ISSN:
年,卷(期):2023.6(3)
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