首页|瑞马唑仑联合艾司氯胺酮在小儿手术中的应用

瑞马唑仑联合艾司氯胺酮在小儿手术中的应用

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选取拟行扁桃体或(和)腺样体切除术的患儿作为研究对象,探究瑞马唑仑联合艾司氯胺酮在小儿扁桃体或(和)腺样体手术中的应用效果.将患儿随机分为观察组(予以瑞马唑仑联合艾司氯胺酮)和对照组(予以丙泊酚联合舒芬太尼),比较两组患儿的平均动脉压、心率、FLACC评分、Aono评分、术后呛咳情况、术后呕吐情况、拔管时间及拔管前追加丙泊酚情况.结果表明,观察组插管时、插管后5 min的平均动脉压及心率均高于对照组的;观察组的拔管时间、拔管前追加丙泊酚例数均明显少于对照组的;观察组的FLACC评分、Aono评分、术后躁动发生率及术后呛咳发生率均明显低于对照组的,但两组术后恶心呕吐发生率无明显差异.说明瑞马唑仑联合艾司氯胺酮在小儿扁桃体或(和)腺样体切除术中的应用效果显著,具有稳定的血流动力学特性,有助于降低围术期低血压风险及术后不良反应发生率,进一步提高患儿苏醒质量.
Application of Remimazolam Combined with Esketamine in Pediatric Surgery
In order to explore the application effect of remimazolam combined with esketamine in tonsil or(and)adenoid surgery in children,children who planned to undergo tonsil or(and)adenoid resection were selected as study objects,and were randomly divided into observation group(given remimazolam combined with esketamine)and control group(given propofol combined with sufentanil).The mean ar-terial pressure,heart rate,FLACC score,Aono score,postoperative coughing,postoperative vomiting,ex-tubation time and propofol addition before extubation were compared between the two groups.The re-sults showed that the mean arterial pressure and heart rate during intubation and 5 min after intubation in observation group were higher than those in control group.The extubation time and the number of propofol addition before extubation in the observation group were significantly less than those in the con-trol group.The FLACC score,Aono score,postoperative agitation rate and postoperative choking rate of the observation group were significantly lower than those of the control group,but the incidence of post-operative nausea and vomiting was not significantly different between the two groups.The application of remimazolam combined with esketamine in tonsillectomy or(and)adenoidectomy in children is effective,has stable hemodynamic characteristics,and helps to reduce the risk of perioperative hypotension,the in-cidence of postoperative adverse reactions,and further improves the recovery quality of children.

remimazolamesketamineagitation during awakeningtonsillectomy

傅严、赵诚、张治猛、黄大元

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吉首大学医学院,湖南 吉首 416000

张家界市人民医院麻醉科,湖南 张家界 427000

瑞马唑仑 艾司氯胺酮 苏醒期躁动 扁桃体切除术

2024

吉首大学学报(自然科学版)
吉首大学

吉首大学学报(自然科学版)

影响因子:0.451
ISSN:1007-2985
年,卷(期):2024.45(2)
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