Determination of Levofloxacin on Carboxylated Multi-Wall Carbon Nanotubes Modified Glassy Carbon Electrode
Electrochemical behavior of levofloxacin on carboxylated multi-walled carbon nanotubes(c-MWCNTs)modified glassy carbon electrode(c-MWCNTs/GCE)was studied,and the content of levo-floxacin was determinated.The results showed that the electrode had good electrocatalysis to levofloxa-cin.In a mixed phosphate(NaH2PO4-Na2HPO4)buffer solution with pH 5.0,the excellent linear rela-tionship was kept between oxidation peak currents and the concentration of levofloxacin in the range of 1×10-5～4×10-4 mol/L with the correlation coefficient of 0.998,and the detection limit of 2.87×10-6 mol/L.Under the optimal test conditions,the recoveries of levofloxacin tablets were 98.7％～103.0％,and the relative standard deviation values of determination results were 1.31％～3.99％(n=5).Thus the c-MWCNTs/GCE has good electrochemical response to levofloxacin with high sensitivity and can be used for determination of levofloxacin content in drugs.
万方数据
维普
