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土家药水黄连的研究现状及临床应用

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为了深入挖掘土家药水黄连的药用潜力,通过查阅中草药典籍及相关文献,从生药鉴定、化学成分、含量测定、提取工艺、药理作用及临床应用6个维度,对水黄连的研究现状进行了较为全面的综述.结果表明,水黄连富含咕吨酮类、环烯醚萜类、三萜类、黄酮类及酚类等多种化学成分,具有抗炎、抗菌、抗肿瘤、抗病毒及抗氧化等多种药理活性;在临床实践中,水黄连被广泛用于治疗肺热、肺炎、黄疸、胆囊炎、急慢性肠炎、妇科炎症、痢疾、腹泻、尿路感染、恶疮疥癣、口腔溃疡等多种疾病,显示出极高的药用价值.
Research Status and Clinical Application of the Tujia Medicinal Swertia davidii
To further explore the medicinal potential of Tujia medicine,this paper comprehensively re-views the research progress of Swertia davidii in six aspects,including crude drug identification,chemi-cal composition,content determination,extraction technology,pharmacological action,and clinical appli-cation,by referring to Chinese herbal medicine classics and related literature.The results indicate that Swertia davidii is abundant in various chemical components,including xanthones,iridoids,triterpenoids,and flavonoids,and exhibits diverse pharmacological activities such as anti-inflammatory,antibacterial,antitumor,antiviral,and antioxidant properties.In clinical practice,Swertia davidii is extensively used in the treatment of pulmonary fever,pneumonia,jaundice,cholecystitis,acute and chronic enteritis,gyneco-logical inflammation,dysentery,diarrhea,urinary tract infections,scabies,oral ulcers,and other diseases,demonstrating significant medicinal value.

Swertia davidiiTujia medicinechemical compositionpharmacological activityclinical ap-plication

何婷湘、符青青、朱家馨、彭胜文、刘芬

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吉首大学药学院,湖南吉首 416000

武陵山区药用资源化学与药理湖南省高校重点实验室,湖南吉首 416000

水黄连 土家药 化学成分 药理活性 临床应用

2024

吉首大学学报(自然科学版)
吉首大学

吉首大学学报(自然科学版)

影响因子:0.451
ISSN:1007-2985
年,卷(期):2024.45(6)