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土家药山姜挥发油对小鼠胃肠动力的影响

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将小鼠分为对照组、大黄组、山姜挥发油5.2 g/kg剂量组、山姜挥发油10.4 g/kg剂量组,通过肠推进试验、排便观察、胃排空试验等探究山姜根茎中的挥发油成分对小鼠肠道推进功能、排便功能、胃排空功能的影响.结果表明,与对照组相比,大黄组、山姜挥发油5.2 g/kg剂量组、山姜挥发油10.4 g/kg剂量组的肠道炭末推进率均有所升高;与对照组相比,大黄组、山姜挥发油5.2 g/kg剂量组、山姜挥发油10.4 g/kg剂量组的首次排黑便时间均有所提前;与对照组相比,大黄组、山姜挥发油5.2 g/kg剂量组、山姜挥发油10.4 g/kg剂量组的胃排空率均有所升高;山姜挥发油10.4 g/kg剂量组的提升作用与大黄组的提升作用相当.这提示山姜挥发油对小鼠的肠推进、排便、胃排空均具有一定的促进作用.
Effects of Volatile Oil of the Alpinia japonica Rhizome on Gastrointestinal Motility of Mice in Tujia Medicine
To investigate the effects of volatile oil of the Alpinia japonica rhizome on the gastrointestinal motility of mice,mice were divided into control group,rhubarb group,volatile oil of the Alpinia japonica rhizome 5.2 g/kg dose group,and volatile oil of the Alpinia japonica rhizome 10.4 g/kg dose group.The effects of volatile oil of the Alpinia japonica rhizome on the intestinal propulsion function,defeca-tion function,and gastric emptying function of mice were explored through intestinal propulsion test,def-ecation observation,and gastric emptying test.The results showed that the charcoal retention rate of the rhubarb group,volatile oil of the Alpinia japonica rhizome 5.2 g/kg dose group,and volatile oil of the Alpinia japonica rhizome 10.4 g/kg dose group was all higher than that of the control group;the first black defecation time of the rhubarb group,volatile oil of the Alpinia japonica rhizome 5.2 g/kg dose group,and volatile oil of the Alpinia japonica rhizome 10.4 g/kg dose group was all earlier than that of the control group;the gastric emptying rate of the rhubarb group,volatile oil of the Alpinia japonica rhizome 5.2 g/kg dose group,and volatile oil of the Alpinia japonica rhizome 10.4 g/kg dose group was all higher than that of the control group;the enhancement effect of volatile oil of the Alpinia japonica rhizome 10.4 g/kg dose group was comparable to that of the rhubarb group.The results suggest that volatile oil of the Alpinia japonica rhizome has certain promoting effects on the intestinal propulsion,defecation,and gastric emptying of mice.

Alpinia japonicavolatile oilgastrointestinal motilityintestinal propulsiondefecationgas-tric emptying

赵京、许太静、罗静、彭清波、高志宏、向娟

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吉首大学药学院武陵山区药用资源化学与药理湖南省高校重点实验室,湖南吉首 416000

土家医药传承与创新实验室国家民委重点实验室,湖南吉首 416000

湖南省土家医药研究中心,湖南吉首 416000

山姜 挥发油 胃肠动力 肠推进 排便 胃排空

2024

吉首大学学报(自然科学版)
吉首大学

吉首大学学报(自然科学版)

影响因子:0.451
ISSN:1007-2985
年,卷(期):2024.45(6)