To explore the impact of Trimethoprim(TMP)on the co-fermentation system of sludge and liquor wastewater,this study investigated the effects of different concentrations of TMP on the co-fermentation system of excess sludge and liquor wastewater over a short period of time(14 d).The mechanism of TMP action on the co-fermentation system was also elucidated.The results indicated that the dosage of TMP positively correlated with VFAs production at low concentrations(0～5 mg/L),although there was a slight decrease in accumulation beyond this range.Analysis of key enzyme activities suggested that TMP promoted dissolution,hydrolysis,and acidification processes in the co-fermentation system while inhibiting methanogenesis.These findings provide valuable insights for the harmless and resource utilization of excess sludge,liquor wastewater and antibiotics.
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