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核酸检测的重排算法及其数值模拟

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2022 年春季上海遭受到奥密克戎变异株的侵袭,核酸检测是筛查新冠阳性病例的重要手段之一。目前社区常用核酸检测方式是 10 人/20 人混合检测,重点人群单人单管复测。考虑到检测数量的庞大,二次复核易对非阳性人员造成恐慌,仿照CT成像原理,设计一种核酸检测重排方法,每人检测后将检测液分别随机置于多组不同试管中,根据不同组试管中的检测结果(投影数据),利用反投影方法,确定进入二次检测人员。计算机仿真结果表明,上述所设计的重排算法能够实现减少总检测数量和提高进入二次检测人员精度的目的。因此以上重排方法有望进一步应用到智能化的核酸采样机器人上,达到高效检测的目的。
Rearrangement Method and Numerical Simulation of Nucleic Acid Detection
In the spring of 2022,Shanghai was invaded by the Omicron mutant.Nucleic acid detection is one of the important means to screen new crown positive cases.At present,the common method of nucleic acid detection in the community is 10/20 persons mixed detection,and the key population is retested by single-person and single-tube.Considering the huge number of tests,and the secondary review is easy to cause panic to non-positive people,this paper designs a nucleic acid detection rearrangement method based on the principle of CT imaging.After each person tests,the test solution is randomly placed in multiple groups of different test tubes.According to the backpro-jection method and the test results(projection data)in different groups of test tubes,the personnel who enter the sec-ondary test are determined.Computer simulation results show that the rearrangement method designed in this paper can reduce the total number of detections and improve the accuracy of secondary detection personnel.Therefore,this method is expected to be further applied to the intelligent nucleic acid sampling robot to achieve the purpose of effi-cient detection.

Image reconstructionRearrangement methodMultiple projectionRandom simulation

王彩芳、张金晓、沈佳杰

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上海海事大学文理学院,上海 201306

图像重建 重排算法 多维投影 随机模拟

2024

计算机仿真
中国航天科工集团公司第十七研究所

计算机仿真

CSTPCD
影响因子:0.518
ISSN:1006-9348
年,卷(期):2024.41(3)
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