首页|基于电网络理论和计算流体力学的血流仿真

基于电网络理论和计算流体力学的血流仿真

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人体的上肢动脉包括肱动脉和桡动脉,两段动脉也经常被作为测得人体血压及脉搏波的关键部位,反映出了丰富的生理病理信息,对此进行研究对心血管疾病的诊断具有着重要意义。对比结合了基于弹性腔的电网络模型法和双向流固耦合计算流体力学模型法,分别建立了在相同结构和力学参数下的两种仿真模型,通过两种方法在不同尺度下的优势互补,对人体在健康及动脉粥样硬化状态下的上肢动脉段的血流动力学问题进行了研究。一方面通过电网络模型对动脉脉搏波进行了动态仿真,发现在动脉粥样硬化下脉搏波的主波波峰出现了明显的升高和前滞现象,另一方面通过双向流固耦合计算流体力学法分析了血液流场的局部特性,从而为粥样硬化等心血管疾病的形成机理及预测提供参考。
Blood Flow Simulation Based on Electrical Network Theory and Computational Fluid Dynamics
The upper extremity arteries of the human body include the brachial artery and the radial artery.These two arteries are often used as the key parts for measuring human blood pressure and pulse wave,reflecting a lot physi-ological and pathological information.We compare and combine the electrical network model method based on the e-lastic cavity and the bidirectional fluid-structure coupling computational fluid dynamics model method.To study the hemodynamics of the upper limb arterial segment in the human body in the healthy and atherosclerotic state,two simu-lation models under the same structural and mechanical parameters are established.On the one hand,the arterial pulse wave is dynamically simulated through the electrical network model,and it is found that the main wave peak of the pulse wave under atherosclerosis has obvious rise and lag.On the other hand,by the the bidirectional fluid-struc-ture coupling computational fluid dynamics method,we analyze the local mechanical properties of the blood flow field such as velocity,pressure,so as to provide references for the formation and prediction of atherosclerosis and other car-diovascular diseases.

Electrical networkComputational fluid dynamicsAtherosclerosisUpper extremity artery

齐天成、张嘉惠、张怀新

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上海交通大学船舶海洋与建筑工程学院,上海 200240

上海交通大学医学院附属仁济医院,上海 200127

电网络 计算流体力学 粥样硬化 上肢动脉

国家自然科学基金上海交通大学"交大之星"计划医工交叉研究基金

52171316YG2019QNA29

2024

计算机仿真
中国航天科工集团公司第十七研究所

计算机仿真

CSTPCD
影响因子:0.518
ISSN:1006-9348
年,卷(期):2024.41(7)
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