Cloud computing has brought a new technological revolution to the IT industry.It has more extensive interop-erability in the network system.Based on cloud computing multi-source comprehensive information high-capacity fast storage algorithm,this study set the read/write process in a heterogeneous scheme,balance the large capacity information load through weighted processing,divide the information storage unit according to the byte length,propose classified storage conditions based on cloud computing,and quickly store multi-source comprehensive information according to the similarity judgment criteria on the premise of a given data storage logical structure.The results show that taking video and audio infor-mation as the test object,sample information can be retrieved according to various attributes,which can be quickly stored under the application of the algorithm in this paper,and the integrity of the data can be guaranteed after conversion,with ap-plication effect.