Olfaction plays a crucial role in the survival and reproduction of organisms.Bio-inspired olfactory models,as a signifi-cant approach to studying smell,have the potential to drive the development of various fields such as biology,neuroscience,en-vironmental monitoring,computer science,and medicine.In addressing the challenges presented by the numerous existing bio-inspired olfactory models,this work initially conducts a comprehensive review of the composition and operation principles of the biological olfactory nervous system,providing a theoretical foundation for constructing bio-inspired olfactory models.Secondly,based on the principle of simulating the binding process between olfactory receptor cells and odor molecules,the methods for con-structing bio-inspired olfactory models are meticulously categorized and summarized.Each method is thoroughly dissected in terms of its working mechanisms and principles,and their strengths and limitations in bio-inspired olfactory model research are summarized.Finally,addressing the issues encountered during the construction of bio-inspired olfactory models,feasible recom-mendations are provided based on theoretical derivations and practical application experiences.