实用临床医药杂志2024,Vol.28Issue(2) :119-123.DOI:10.7619/jcmp.20233010

右美托咪定作为神经阻滞佐剂的研究进展

Research progress of dexmedetomidine as an adjuvant for nerve block

张文洁 屈松 吴玉敏 阎文军
实用临床医药杂志2024,Vol.28Issue(2) :119-123.DOI:10.7619/jcmp.20233010

右美托咪定作为神经阻滞佐剂的研究进展

Research progress of dexmedetomidine as an adjuvant for nerve block

张文洁 1屈松 1吴玉敏 1阎文军2
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作者信息

  • 1. 甘肃中医药大学第一临床医学院,甘肃兰州,730000
  • 2. 甘肃省人民医院麻醉科,甘肃兰州,730000
  • 折叠

摘要

神经阻滞是一种麻醉和疼痛管理技术,其通过局部麻醉药物在特定神经区域阻断神经传导来实现.神经阻滞与全身麻醉相比具有许多优势,可以提供局部和选择性的镇痛效果,同时减少全身麻醉相关的并发症和药物副作用.右美托咪定是一种α2肾上腺素受体激动剂,作为潜在的佐剂,被广泛用于神经阻滞中.右美托咪定具有镇静、镇痛和抗焦虑的效果,可以与局部麻醉药物结合使用,以增强神经阻滞的效果.本研究将右美托咪定作为各个部位神经阻滞佐剂的临床作用进行综述,新增了其在颌面部神经阻滞和星状神经节阻滞中的运用,为神经阻滞麻醉和镇痛提供参考.

Abstract

Nerve block is a technique for anesthesia and pain management,which is realized by blocking nerve conduction in a specific nerve area with local anesthetic drugs.Compared with general anesthesia,nerve block has many advantages,which can provide local and selective analgesic effect,and meanwhile reduce complications and drug side effects related to general anesthesia.Dexmedeto-midine is a type of α2 adrenergic receptor agonist,and as a potential adjuvant,dexmedetomidine has been widely applied in nerve block.Dexmedetomidine has sedative,analgesic and anti-anxiety effects,and can be used in combination with local anesthetics to enhance the effect of nerve block.In this paper,the clinical effects of dexmedetomidine as an adjuvant of nerve block in various parts are reviewed,and application in maxillofacial nerve block and stellate ganglion block was added in order to provide reference for nerve block anesthesia and analgesia.

关键词

右美托咪定/神经阻滞/佐剂/麻醉/手术

Key words

dexmedetomidine/nerve block/adjuvants/analgesia/surgery

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基金项目

国家自然科学基金(81860233)

甘肃省自然科学基金(21JR7RA621)

甘肃省麻醉与脑功能临床医学研究中心(21JR7RA675)

出版年

2024
实用临床医药杂志
扬州大学,中国高校科技期刊研究会

实用临床医药杂志

CSTPCD
影响因子:1.543
ISSN:1672-2353
参考文献量34
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