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高原地区多发性骨髓瘤伴高淀粉酶患者1例分析

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多发性骨髓瘤(MM)是一种恶性浆细胞疾病,临床常表现为骨痛、贫血等症状.目前,关于恶性肿瘤合并高淀粉酶血症文献报道渐多,但多见于胃癌等肿瘤,MM伴高淀粉酶血症临床较少见,高原地区尚未发现.MM伴高淀粉酶血症患者因临床表现复杂,治疗尚无标准方案,未发现达雷妥尤单抗药物联合使用的文献报道.根据首例高原地区MM伴高淀粉酶血症的回顾分析结果,建议高原地区临床医生将淀粉酶水平作为MM患者病情严重程度的敏感指标,以降低MM的误诊率,并提供一种MM伴高淀粉酶血症疾病中新的治疗方案.
Multiple myeloma with high amylase in high altitude areas:a case report
Multiple myeloma(MM)is a malignant plasmacyte disease that often presents with symptoms such as bone pain and anemia.Currently,there is an increasing number of literature re-ports on malignant tumors combined with hyperamylasemia,but this is more common in tumors such as gastric cancer,and MM with hyperamylasemia is clinically rare and has not been found in plateau areas.Due to the complex clinical manifestations of MM patients with hyperamylasemia,there is no standard treatment therapy.There is no literature report on the use of daretuumab in combination.Based on the results of the retrospective analysis of the first case of MM with hyperamylasemia in a plateau area,it is recommended that clinicians in plateau areas take amylase level as a sensitive indi-cator to evaluate the severity of MM in order to reduce the misdiagnosis rate of MM and provide a new treatment option for the promotion and application of MM with hyperamylasemia.

multiple myelomahyperamylasemiaplateaudaratumumab

李胜学、王晓莉、丛萌倩、殷玉娟

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青海大学附属医院检验科,青海,西宁,810001

青海大学附属医院血液科,青海,西宁,810001

多发性骨髓瘤 高淀粉酶血症 高原 达雷妥尤单抗

2024

实用临床医药杂志
扬州大学,中国高校科技期刊研究会

实用临床医药杂志

CSTPCD
影响因子:1.543
ISSN:1672-2353
年,卷(期):2024.28(5)
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