Objective To observe the therapeutic effect of laparoscopic sleeve gastrectomy(LSG)in treating patients with obesity and polycystic ovary syndrome(PC OS).Methods In this ret-rospective analysis,clinical materials of 60 patients with obesity and PCOS by LSG were analyzed,and postoperative improvements of PCOS symptoms were observed.Results A total of 60 patients had a pre-operative mean body mass index(BMI)of(39.4±5.4)kg/m2 and an average age of(26.3±6.1)years old,and all of them successfully completed LSG.After follow-up of 12 to 18 months,50 cases(83.3%)had normalized menstrual cycles,with an average recovery time of(4.5±2.2)months af-ter surgery,and 7 cases had natural pregnancy after surgery.Before surgery,ultrasound results in 35 patients indicated polycystic ovarian morphology(PCOM),and 29 cases(82.9%)regained normal o-varian status with an average recovery duration of(6.3±2.8)months.Complicated hyperandrogene-mia was observed in 31 patients,and 29 cases(93.5%)exhibited normalization of testosterone levels within 18 months after surgery.At 18 months after surgery,the BMI was(26.47±4.70)kg/m2,the average weight loss was(32.4±7.4)%.Conclusion LSG is a safe and effective treatment for obese PCOS.