实用临床医药杂志2024,Vol.28Issue(10) :35-38,50.DOI:10.7619/jcmp.20233205

美国麻醉医师协会分级在局部麻醉经皮肾镜碎石取石术的上尿路结石患者中的应用评价

Application of the American Society of Anesthesiologists classification in treating patients with percutaneous nephrolithotomy under local anesthesia for upper urinary tract calculi

胡小剑 党晓平 郑亮 张志刚 牛彬 倪锋 党建功
实用临床医药杂志2024,Vol.28Issue(10) :35-38,50.DOI:10.7619/jcmp.20233205

美国麻醉医师协会分级在局部麻醉经皮肾镜碎石取石术的上尿路结石患者中的应用评价

Application of the American Society of Anesthesiologists classification in treating patients with percutaneous nephrolithotomy under local anesthesia for upper urinary tract calculi

胡小剑 1党晓平 2郑亮 1张志刚 1牛彬 1倪锋 1党建功1
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作者信息

  • 1. 西安医学院第二附属医院泌尿外科,陕西西安,710038
  • 2. 西安医学院第二附属医院新生儿科,陕西西安,710038
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摘要

目的 分析美国麻醉医师协会(ASA)分级在行局部麻醉经皮肾镜碎石取石术(PCNL)的上尿路结石患者中的应用价值.方法 将80例行局部麻醉PCNL的上尿路结石患者根据ASA分级分为高危组(ASA分级Ⅲ~Ⅳ级)36例和低危组(ASA分级Ⅰ~Ⅱ级)44例,比较2组围术期指标(手术时间、术中出血量、住院时间)、结石清除率、炎性因子[C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]、疼痛视觉模拟评分法(VAS)评分及并发症发生率.结果 低危组住院时间短于高危组,差异有统计学意义(P<0.05);低危组结石清除率为93.18%,高于高危组的75.00%,差异有统计学意义(P<0.05).术前,高危组血清CRP、IL-6、TNF-α水平高于低危组,差异有统计学意义(P<0.05);术后1 d,高危组术后血清CRP、IL-6、TNF-α水平高于低危组,差异有统计学意义(P<0.05).术后1、3、5 d时,高危组和低危组VAS评分均降低,且低危组VAS评分低于高危组,差异有统计学意义(P<0.05).低危组并发症发生率为4.54%,低于高危组的19.44%,差异有统计学意义(P<0.05).结论 局部麻醉PCNL治疗ASA分级Ⅰ~Ⅱ级的上尿路结石患者的炎症反应、疼痛程度较ASA分级Ⅲ~Ⅳ级患者轻,且并发症发生率低.

Abstract

Objective To analyze the application value of the American Society of Anesthesiolo-gists(ASA)classification in treating patients with percutaneous nephrolithotomy(PCNL)under local anesthesia for upper urinary tract calculi.Methods A total of 80 patients with PCNL under local an-esthesia for upper urinary tract calculi were divided into high-risk group(ASA Ⅲ to Ⅳ level)with 36 cases and low-risk group(ASA Ⅰ to Ⅱ level)with 44 cases according to ASA classification,and perioperative indicators(operation time,intraoperative blood loss and hospital stay),stone clearance rate,inflammatory factors[C reactive protein(CRP),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)],score of the Visual Analogue Scale(VAS)for pain,and the incidence of complications were compared between the two groups.Results Hospital stay in the low-risk group was significantly shorter than that in the high-risk group(P<0.05);the stone clearance rate was 93.18%in the low-risk group,which was significantly higher than 75.00%in the high-risk group(P<0.05).Before sur-gery,the levels of serum CRP,IL-6 and TNF-α in the high-risk group were significantly higher than those in the low-risk group(P<0.05);one day after surgery,the levels of serum CRP,IL-6 and TNF-α in the high-risk group were significantly higher than those in the low-risk group(P<0.05).On the first,the third,and the fifth day after surgery,the VAS score in the high-risk and low-risk groups decreased significantly,and the VAS score in the low-risk group was significantly lower than that in the high-risk group(P<0.05).Incidence rate of complications in the low-risk group was 4.54%,which was significantly lower than 19.44%in the high-risk group(P<0.05).Conclu-sion Application of PCNL under local anesthesia in treating patients with upper urinary tract calculi of ASA Ⅰ to Ⅲ has milder inflammation and pain when compared to those of ASA Ⅲ to Ⅳ,and the incidence rate of complications is relatively low.

关键词

美国麻醉医师协会分级/局部麻醉/经皮肾镜碎石取石术/上尿路结石/炎症反应/并发症

Key words

the American Society of Anesthesiologists classification/local anesthesia/percu-taneous nephrolithotomy/upper urinary tract calculi/inflammatory response/complications

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基金项目

陕西省卫生健康科研项目(2022E029)

西安医学院院级科研项目(22KY0110)

出版年

2024
实用临床医药杂志
扬州大学,中国高校科技期刊研究会

实用临床医药杂志

CSTPCD
影响因子:1.543
ISSN:1672-2353
参考文献量11
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