Objective To observe the application effect of double balloon enteroscopy(DBE)in polypectomy.Methods Clinical materials of 34 patients with DBE assisted polypectomy for small in-testinal polyps were retrospectively analyzed,and the experience in using various accessories during DBE assisted polypectomy as well as various preventive measures for complications such as perfora-tion,bleeding,abdominal distension and pain were summarized.Results Among the 34 patients,except for one patient who was converted to surgical operation due to excessive polyps blocking the in-testinal lumen,the other 33 patients successfully completed the DBE assisted polypectomy for small intestinal polyps;one patient suffered from delayed hemorrhage and successfully stopped bleedingun-der endoscopy,with a complication rate of 3.0%.All the patients were discharged smoothly after careful nursing,with an average hospital stay of(2.21±0.47)days.Conclusion The polypectomy under DBE is safe and reliable in the resection of intestinal polyps.Sufficient preoperative prepara-tion,good intraoperative cooperation between doctors and nurses,skilled operation,and strict postop-erative observation are important guarantees for the success of intestinal polyp resection under DBE,which can reduce the incidence rate of complications and promote the recovery of patients.