Impact of stenting at the origin of vertebral artery on cognitive function in patients with first-onset temporal or thalamic infarction
Objective To investigate the impact of stenting at the origin of vertebral artery(VAO)on cognitive function in patients with first-onset temporal or thalamic infarction.Methods A total of 65 patients with first-onset temporal or thalamic infarction were selected as research subjects,and were diagnosed with new-onset infarction in the medial temporal lobe or thalamus by craniocere-bral magnetic resonance imaging(MRI),and severe stenosis of VAO as the responsible vessel for in-farction was confirmed by head and neck computed tomography angiography(CTA).A total of 35 pa-tients who received VAO stenting were included in the stenting group,and 30 patients who received drug-based conservative treatment were included in the control group.The Montreal Cognitive Assess-ment Scale(MoCA),Wechsler Adult Intelligence Scale-Digit Span Test(WAIS-DS),and Fuld Ob-ject Memory Evaluation Scale(FOM)scores were compared between the two groups before treatment,14 days and 3 months after treatment.Results Before treatment,there was no significant difference in the scores of each scale between the two groups(P＞0.05).At 14 days and 3 months after treat-ment,the total MoCA score and the scores of visual space and executive function,delayed recall,and language dimension in the stenting group were higher than those in the control group(P＜0.05).The FOM score in the stenting group was higher than that in the control group at 3 months after treat-ment(P＜0.05).Conclusion Stenting can significantly improve the cognitive function of patients with temporal lobe and thalamic infarction.
vertebral artery stentorigin of vertebral arterytemporal lobe infarctiontha-lamic infarctioncognitive function
万方数据
维普
