自身免疫性肝病发病机制的研究进展
Research progress on pathogenesis of autoimmune liver diseases
李娟 1哈小琴 1卢利霞2
作者信息
- 1. 中国人民解放军联勤保障部队第九四○医院,检验科,甘肃兰州,730050
- 2. 中国人民解放军联勤保障部队第九四○医院,消化内科,甘肃兰州,730050
- 折叠
摘要
自身免疫性肝病(AILD)是一组病因不明,免疫介导的慢性肝脏损伤性疾病.该类疾病的发病机制目前尚不明确,临床表现具有非特异性,较难确诊,对人类生命健康长期存在严重威胁.现将AILD发病机制的研究进展综述如下,以期为AILD的临床诊疗提供新靶点和有力证据.
Abstract
Autoimmune liver diseases(AILD)represent a group of chronic,immune-mediated liver injuries with unknown etiology.The pathogenesis of these diseases remains elusive,and their clinical manifestations are non-specific,posing significant challenges for accurate diagnosis and long-term threats to human health.Therefore,the pathogenesis of AILD was reviewed,aiming to provide novel targets and robust evidence for clinical diagnosis and treatment of AILD.
关键词
自身免疫性肝病/原发性胆汁性胆管炎/原发性硬化性胆管炎/发病机制Key words
autoimmune liver disease/primary biliary cholangitis/primary sclerosing cholan-gitis/pathogenesis引用本文复制引用
基金项目
中央高校基本科研业务费项目(31920200020)
出版年
2024
国家科技期刊平台
NSTL
万方数据