Progress in diagnosis and treatment of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction(HFpEF)is defined as having a left ven-tricular ejection fraction(LVEF)of ≥50%accompanied by elevated natriuretic peptide(BNP)levels or other evidence of congestion.HFpEF is characterized by high morbidity and mortality rates and has surpassed heart failure with reduced ejection fraction(HFrEF)to become the predominant form of heart failure.This article reviewed the definition,epidemiology,classification,diagnosis,pathology,comorbidities,and treatment of HFpEF,providing evidence for clinical research.
heart failure with preserved ejection fractionheart failure with reduced ejection fractionheart failureinflammationendothelial dysfunctiondiastolic dysfunction