Application effect of fiberoptic bronchoscopy and alveolar lavage therapy in diagnosis and treatment of recurrent wheezing disorders in children
Objective To investigate the application effect of fiberoptic bronchoscopy and alveolar lavage therapy in the diagnosis and treatment of recurrent wheezing diseases in children.Methods A total of 151 children with recurrent wheezing diseases were enrolled,and divided into control group(n=84)and study group(n=67)based on different diagnostic and therapeutic methods.The control group received conventional diagnosis and treatment,while the study group underwent fiberoptic bron-choscopy combined with alveolar lavage therapy.The time to resolution of symptoms and length of hos-pital stay were compared between the two groups.Additionally,lung function[forced expiratory vol-ume in 1 second(FEV1),FEV1/forced vital capacity(FEV1/FVC)and peak expiratory flow(PEF)],exhaled nitric oxide(FeNO),serum inflammatory mediator levels[C-reactive protein(CRP),procalcitonin(PCT)and white blood cell(WBC)count]and clinical efficacy were com-pared.Results The absence time of wheezing and pulmonary rales and hospital stay in the study group were significantly shorter than those in the control group(P＜0.05).After treatment,FEV1,FEV1/FVC and PEF in two groups were significantly higher than before treatment,and the study group was significantly higher than the control group(P＜0.05).After treatment,FeNO,CRP,PCT and WBC in two groups were significantly lower than before treatment,and the study group was significantly lower than the control group(P＜0.05).The total effective rate of the study group was 94.03％,which was significantly higher than 77.38％of the control group(P＜0.05).Conclusion Fiber-optic bronchoscopy and alveolar lavage are effective in the diagnosis and treatment of recurrent asth-matic diseases in children,which can effectively relieve symptoms,shorten hospital stay,and im-prove lung function,FeNO and serum inflammatory mediators.
fiberoptic bronchoscopyalveolar lavage therapyrecurrent wheezing diseases in childrenserum inflammatory mediatorslung function
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维普
