The process flow of petrochemical industries is complex and there are many produc-tion devices.The water quality and quantity of the petrochemical wastewaters treatment system fluctuate greatly,making it difficult to respond to regulation in a timely manner,resulting in fre-quent impacts on downstream wastewater treatment systems.This study is based on real water quality data of homogeneous pool effluent,conduct correlation analysis and feature dimensionality reduction on water quality parameters,and constructs a multi parameter water quality prediction model and a time series water quality prediction model.The research results indicate that there is a certain correlation between conductivity(Cond)and COD(PCC and SCC are 0.493 and 0.513,re-spectively),and the correlation order between various water quality parameters and COD is Cond>pH>NH3-N>TP.SVR and BP-ANN multi parameter prediction models did not achieve ideal pre-diction results,with determination coefficients R2 both below 0.5;The SVR and BP-ANN time se-ries models have higher prediction accuracy,and the parameter model has significantly improved.The coefficient of determination R2 has increased by an average of 45%,both higher than 0.7,the predicted values are consistent with the measured values and have a high degree of fit;The on-site verification results of the model indicate that when the upstream wastewaters quality fluctuates,model can accurately predict the trend of water quality fluctuations and effectively guide the on-site regulation of process parameters.