Comparative Study of the Effects of Nano ZnO and CuO on the Biodegradation,Biocompatibility,and Antibacterial Properties of Micro-arc Oxidation Coating of Magnesium Alloy

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外文摘要：This research systematically examined the degradation,antibacterial effects,and biocompatibility of micro-arc oxidation(MAO)coatings with nano CuO and ZnO on extruded Mg alloys.Both copper(Cu)and Zinc(Zn)possess antibacterial properties.The findings demonstrated that adding ZnO will appreciably reduce the degradation rate of MAO-coating alloy due to the self-sealing micro holes.CuO+MAO coating exhibited excellent antibacterial performance,with an antibacterial rate of over 90％within 6 h co-cultured with Staphylococcus aureus.Similarly,the antibacterial rate of ZnO+MAO coating reached 90％after 12 h co-culture.Cytotoxicity test using MG63 cell indicated that the incorporation of CuO and ZnO did not notably affect the cell viability rate of the coating.Moreover,after 14 days of culture,the CuO+MAO and ZnO+MAO coated samples exhibited higher alkaline phosphatase(ALP)activity than the MAO-coated and uncoated samples,suggest-ing favorable osteogenic properties.

外文关键词：

Copper oxideZinc oxideMicro-arc oxidation(MAO)coatingCorrosion behaviorAntibacterial characteristics

作者：

Ying Shen、Xianfeng Shan、Iniobong P.Etim、Muhammad Ali Siddiqui、Yang Yang、Zewen Shi、Xuping Su、Junxiu Chen

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作者单位：

Key Laboratory of Materials Surface Science and Technology of Jiangsu Province,Changzhou University,Changzhou 213164,China

Department of Stomatology,The Affiliated Xinhua Hospital of Dalian University,Dalian 116000,China

Department of Physics,University of Calabar,Calabar 540242,Nigeria

Metallurgical Engineering Department,NED University of Engineering and Technology,University Road,Karachi 75270,Pakistan

Ningbo No.2 Hospital,Ningbo 315010,China

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基金：

国家自然科学基金中国博士后科学基金Major Project of 2025 Sci & Tech Innovation of Ningbo

项目编号：

520010342023M7316772020Z096

出版年：

2024

DOI：

10.1007/s40195-023-01627-3

金属学报(英文版)

中国金属学会

金属学报(英文版)

CSTPCD

影响因子：0.77

ISSN：1006-7191

年,卷(期)：2024.37(2)

参考文献量49