Distribution and antimicrobial resistance of 479 methicillin-resistant Staphylococcus aureus isolates in a hospital
Objective To analyze retrospectively the detection,distribution and antimicrobial resistance of methicillin-resistant Staphylococcus aureus(MRSA)among inpatients in Suqian First People's Hospital,so as to provide insights into the effective manage-ment of nosocomial infections.Methods MRSA isolates from inpatients in Suqian First People's Hospital from 2019 to 2022 were collected using the Xinglin nosocomial infection surveillance system and statistically analyzed.Results A total of 1 054 Staphylococ-cus aureus isolates were collected,including 479 MRSA isolates,with a mean detection rate of 45.45％.The five most common depart-ments where MRSA isolates were distributed included Department of Pediatrics(18.16％),Department of Critical Care Medicine(16.70％),Department of General Surgery(9.60％),Department of Traditional Chinese Medicine and Bums(8.77％),and Department of Otolaryngology and Stomatology(7.72％),and the clinical samples were mainly derived from sputum(49.06％)and wound secretions(35.07％).The sites of infections mainly included lower respiratory tract(48.85％)and skin and soft issues(16.08％),and community-acquired infection was the predominant type of infections(51.77％),followed by nosocomial infection(14.61％)and colonization(33.61％).Community-acquired infection was predominant in Department of Neonatology and Department of Pediatrics,and nosocomial infection was predominant in Department of Neurosurgery and Department of Critical Care Medicine.MRSA was 100.00％resistant to cefoxitin,penicillin and oxacillin,and the prevalence of quinolones resistance was less than 9％in MRSA.In addition,the prevalence of erythromycin and clindamycin resistance was more than 60％in MRSA,and the prevalence of tige-cycline,vancomycin,linazolamide and nitrofurantoin was all 0 in MRSA.Conclusions The detection of MRSA is high in Suqian First People's Hospital,and MRSA shows different levels of resistance to common antimicrobial agents.Intensified supervision of pre-ventive measures is required in departments with high detection of MRSA and high incidence of nosocomial infections by department of infection control,in order to reduce the infection and spread of MRSA in the hospital.
NETL
NSTL
万方数据
