Prevalence of SARS-CoV-2 infections and protective effect of COVID-19 vaccines among workers in disease control and prevention institutions in Tongren City during the SARS-CoV-2 infection
Objective To investigate the prevalence of SARS-CoV-2 infections and protective effect of COVID-19 vaccines among workers in disease control and prevention institutions following the COVID-19 pandemic.Methods An internet-based questionnaire survey was performed in city-and county-level disease control and prevention institutions in Tongren City in February,2023.The records of nucleic acid tests and vaccinations were retrieved,and the characteristics of SARS-CoV-2 infections and vaccination were analyzed a-mong in-service employees.Results A total of 682 valid questionnaires were recovered,with an effective response rate of 93.2％.The overall prevalence of SARS-CoV-2 infections was 88.71％among the respondents,and there was a gender-specific prevalence rate of SARS-CoV-2 infections(X2=21.58,P＜0.01).The symptoms of SARS-CoV-2 infections mainly included fever,weakness and systemic soreness and pain,and the proportions of weakness,dizziness/headache,throat dryness and itching and hypogeusia were all higher a-mong confirmed cases than among suspected cases(all P values＜0.05),and there was a significant difference in the prevalence of SARS-CoV-2 infections between respondents with and without a history of smoking(77.24％vs.91.81％;x2=24.18,P＜0.01).In addi-tion,there were significant differences between respondents with and without SARS-CoV-2 infections in terms of doses of different COV-ID-19 vaccines,duration from the last vaccination and delivery routes of booster vaccination(all P values＜0.01).Conclusions There is a high rate of SARS-CoV-2 infections among worker in disease control and prevention institutions at different levels,and boost-er doses for COVID-19 vaccination and sequential vaccination may reduce the risk of SARS-CoV-2 infections.A second booster dose and improved coverage of COVID-19 vaccination are strongly recommended to build a solid immune barrier in humans.
Worker in disease control and prevention institutionsSARS-CoV-2 infectionEpidemiological characteristicsVaccination
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