江苏医药2024,Vol.50Issue(1) :26-28,33.DOI:10.19460/j.cnki.0253-3685.2024.01.006

子痫前期合并胎儿生长受限的妊娠结局及危险因素分析

An analysis of pregnancy outcome and risk factors of preeclampsia complicated with fetal growth restriction

余晓红 周飞飞 陈海迎 李凤英 周庆调
江苏医药2024,Vol.50Issue(1) :26-28,33.DOI:10.19460/j.cnki.0253-3685.2024.01.006

子痫前期合并胎儿生长受限的妊娠结局及危险因素分析

An analysis of pregnancy outcome and risk factors of preeclampsia complicated with fetal growth restriction

余晓红 1周飞飞 1陈海迎 1李凤英 1周庆调1
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作者信息

  • 1. 325000 浙江,温州市人民医院妇产科
  • 折叠

摘要

目的 探讨子痫前期合并胎儿生长受限(FGR)的妊娠结局及危险因素.方法 根据是否合并FGR,将子痫前期孕妇162例分为子痫前期合并FGR(观察组,73例)和不合并FGR(对照组,89例)两组,分析两组孕妇及新生儿资料.结果 与对照组比较,观察组母亲胸腔或腹腔积液发生率升高(P<0.05).与对照组比较,观察组新生儿严重并发症、住院时长超过30d和新生儿死亡比例均升高(P<0.05).多因素logistic回归分析结果显示,发病时BMI低、发病孕周小及24-h尿蛋白≥2.0g是子痫前期合并FGR的独立危险因素(P<0.05).结论 子痫前期合并FGR更容易导致母亲和新生儿不良结局,对有高危因素的子痫前期孕妇需加强监测.

Abstract

Objective To investigate the pregnancy outcome and risk factors of preeclampsia complicated with fetal growth restriction(FGR).Methods According to whether FGR was combined,162 pregnancy women diagnosed with preeclampsia were divided into two groups of A(with FGR,73 cases)and B(without FGR,89 cases).The data of pregnant women and newborns of the two groups were analyzed.Results Compared with group B,group A had higher incidence of pleural or abdominal fluid(P<0.05).The proportions of the neonates with serious complications,neonatal death and longer hospital stay(over 30 days)were higher in group A than those in group B(P<0.05).Multivariate logistic regression analysis showed that low BMI at onset,small gestational age and 24-h urinary protein≥2.0 g were independent risk factors for preeclampsia complicated with FGR(P<0.05).Conclusion Preeclampsia with FGR is more likely to lead to adverse maternal and neonatal outcomes.The pregnant women exhibiting high-risk factors for preeclampsia need a enhanced monitoring.

关键词

子痫前期/胎儿生长受限/孕周

Key words

Preeclampsia/Fetal growth restriction/Gestational age

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基金项目

温州市基础性科研项目(Y20210347)

出版年

2024
江苏医药
江苏省人民医院(南京医科大学第一附属医院)

江苏医药

影响因子:0.707
ISSN:0253-3685
参考文献量12
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