Clinical efficacy of neuromuscular electrical stimulation combined with low molecular weight heparin in the prevention of lower limb venous thrombosis in patient with hypertensive intracerebral hemorrhage and hemiplegia
Objective To observe the clinical efficacy of neuromuscular electrical stimulation combined with low molecular weight heparin in the prevention of lower limb venous thrombosis in the patients with hypertensive intracerebral hemorrhage and hemiplegia.Methods A total of 120 patients with hypertensive intracerebral hemorrhage and hemiplegia were equally randomized into two groups of A and C.The patients in group A accepted the neuromuscular electrical stimulation combined with low molecular weight heparin,while whose in group C only received the neuromuscular electrical stimulation.The incidence of lower limb venous thrombosis,blood flow velocities of popliteal and femoral vein,D-dimer level,platelet count and coagulation index(CI)were compared between groups of A and C.Results The incidences of deep and intermuscular venous thrombosis in group A were higher than those in group C(P＜0.05).Compared with before neuromuscular electrical stimulation,the blood flow velocities of popliteal and femoral vein were increased in both groups during the neuromuscular electrical stimulation(P＜0.05),whereas there was no statistical difference in the blood flow velocities of popliteal and femoral vein between groups of A and C(P＞0.05).Compared with admission,the D-dimer level and platelet count were increased on the 7th day after the neuromuscular electrical stimulation in group A(P＜0.05),while the CI,D-dimer level and platelet count were all increased on the 3rd and 7th day after the neuromuscular electrical stimulation in group C(P＜0.05).Moreover,the CI,D-dimer level and platelet count on the 3 rd and 7th day after the neuromuscular electrical stimulation in group A were lower than those in group C(P＜0.05).Conclusion Compared to neuromuscular electrical stimulation,combined use of low molecular weight heparin treatment can effectively prevent the lower limbs venous thrombosis in the patients with hypertensive intracerebral hemorrhage and hemiplegia.
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