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急性缺血性脑卒中患者血管内治疗预后的影响因素分析

An analysis of influencing factors for prognosis of patients with acute ischemic stroke after intravascular therapy

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目的 分析急性缺血性脑卒中患者血管内治疗预后的影响因素.方法 行血管内治疗的急性缺血性脑卒中患者205例,依据改良Rankin量表(mRS)评分将患者分为预后良好组(mRS评分≤2分,57例)和预后不良组(mRS评分≥3分,148例),比较两组患者临床资料,采用多因素logistic回归分析急性缺血性脑卒中患者血管内治疗预后的影响因素,绘制ROC曲线分析临床指标的预测价值.结果 与预后良好组比较,预后不良组患者年龄较大,术前格拉斯哥昏迷评分(GCS评分)、术前Hb和术后三酰甘油较低,女性和合并心房颤动比例、术前美国国立卫生研究院卒中量表(NIHSS)评分、术前溶栓比例、术前白细胞计数、术前中性粒细胞百分比、术后白细胞计数、术后中性粒细胞百分比、术后降钙素原、术后CRP、术后留置胃管比例、急性缺血性脑卒中相关性肺炎评分较高(P<0.05).术前NIHSS评分、术前中性粒细胞百分比和术后CRP较高是急性缺血性脑卒中患者血管内治疗预后不良的独立危险因素(P<0.05),男性和术前Hb较高是其保护性因素(P<0.05).术前NIHSS评分、术前中性粒细胞百分比、术前Hb和术后CRP预测急性缺血性脑卒中患者血管内治疗预后不良的AUC分别为0.833、0.735、0.690和0.714,其相应的预测预后不良的灵敏度分别为 89.5%、59.6%、77.2%和 89.5%,特异度分别为 62.2%、81.8%、54.1%和 51.4%.结论 性别、术前NIHSS评分、术前中性粒细胞百分比、术前Hb和术后CRP是急性缺血性脑卒中患者血管内治疗预后的影响因素.
Objective To analyze the influencing factors for the prognosis of the patients with acute ischemic stroke after intravascular therapy.Methods A total of 205 patients with acute ischemic stroke underwent intravascular therapy were divided into two groups of A[modified Rankin scale(mRS)score<2 points,57 cases]and B(mRS score≥3 points,148 cases).The clinical data of the two groups were compared.The risk factors for the prognosis of the patients with acute ischemic stroke underwent intravascular therapy were analyzed by multivariate logistic regression,and the predictive value of clinical indicators was analyzed by ROC curve.Results Compared to group A,the age was older,the Glasgow Coma Scale score(GCS score),Hb before surgery and triglyceride after surgery were lower,and the proportions of women and the patients with atrial fibrillation,preoperative National Institutes of Health Stroke Scale(NIHSS)score,preoperative thrombolytic proportion,preoperative white blood cell count,preoperative neutrophil percentage,postoperative white blood cell count,postoperative neutrophil percentage,postoperative procalcitonin,postoperative CRP,proportion of postoperative gastric intubation,and acute ischemic stroke-associated pneumonia score were higher ingroup B(P<0.05).Higher preoperative NIHSS score,preoperative neutrophil percentage and postoperative CRP were the independent risk factors for poor prognosis of the patients with acute ischemic stroke underwent intravascular therapy,while male and higher preoperative Hb were the protective factors(P<0.05).The AUC values of preoperative NIHSS score,preoperative neutrophil percentage,preoperative Hb and postoperative CRP for predicting poor prognosis of the patients with acute ischemic stroke underwent intravascular therapy were 0.833,0.735,0.690 and 0.714,respectively,the sensitivity was 89.5%,59.6%,77.2%and 89.5%,respectively,and the specificity was 62.2%,81.8%,54.1%and 51.4%,respectively.Conclusion Gender,preoperative NIHSS score,preoperative neutrophil percentage,preoperative Hb and postoperative CRP are the prognostic factors for the patients with acute ischemic stroke underwent intravascular therapy.

Acute ischemic strokeIntravascular therapyPrognosis

陆懿瑶、王静莹、蒋永泼、杨超

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318050 浙江省台州医院[台州市恩泽医疗中心(集团)恩泽医院]急诊科

急性缺血性脑卒中 血管内治疗 预后

2024

江苏医药
江苏省人民医院(南京医科大学第一附属医院)

江苏医药

影响因子:0.707
ISSN:0253-3685
年,卷(期):2024.50(2)
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