Objective To analyze the clinical and pathological features of 38 cases with squamous cell carcinoma detected in serosal effusion samples.Methods The clinical data of 38 patients with squamous cell carcinoma detected in serosal effusion specimens were collected.The serosal effusion specimens were examined with immunohistochemical EnVision staining,clinical and pathological characteristics were analyzed,and relevant literatures were reviewed.Results The primary lesions of squamous cell carcinoma were diverse,and most commonly occurred in the lungs.The elevated levels of serum tumor markers were helpful in diagnosis.In cell liquid-based smears and cell wax sections,heterokeratinized squamous cell and spiral cell clusters were the diagnostic markers of squamous cell carcinoma.Immunohistochemical markers including p63,cytokeratin 5/6 and p40 were helpful for diagnosis and differential diagnosis.Conclusion Immunohistochemical staining combined with clinical history and cytomorphological features are the keys to improve the detection rate of squamous cell carcinoma in serosal effusion samples.
NETL
NSTL
万方数据
