The value of thromboelastography and routine coagulation tests in diagnosis of lower limbs deep venous thrombosis after cerebrovascular disease surgery
Objective To investigate the diagnostic value of thromboelastography(TEG)and routine coagulation tests in the formation of deep venous thrombosis(DVT)in the lower limbs after cerebrovascular disease surgery.Methods The clinical data of 60 patients underwent deep vein examination of the lower limbs after cerebrovascular disease surgery were retrospectively analyzed.The patients were divided into two groups of A(with DVT formation,33 cases)and C(without DVT formation,27 cases).TEG and conventional coagulation function indexes were compared between the two groups,and the diagnostic value of TEG and conventional coagulation function indexes in the formation of the lower limbs DVT formation was analyzed.Results Fibrinogen(Fib),D-dimer(D-D)and coagulation rate(α angle)were higher,while coagulation time(K value)was lower in group A than those in group C(P＜0.05).The AUC values under the ROC curves formed by Fib,D-D,α angle and K value in the diagnosis of lower limbs DVT formation were 0.68,0.65,0.67 and 0.66,respectively.When the optimal diagnostic cut-off values of Fib,D-D,α angle and K value were 3.22 g/L,732 ng/mL,69.9 degrees and 1.3 minutes,the sensitivity for diagnosing lower limbs DVT formation was 54.5％,60.6％,78.8％and 72.7％,and the specificity was 81.5％,74.1％,59.3％and 59.3％,respectively.Conclusion Both TEG and conventional coagulation tests have certain diagnostic value for the formation of DVT in the lower limbs after cerebrovascular disease surgery.
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万方数据
