Objective To explore the clinical significance of blood indicators in spontaneous intracerebral hemorrhage(sICH).Methods The blood indicators were detected in 117 patients with sICH.The neutrophil to lymphocyte ratio(NLR)and platelet to lymphocyte ratio(PLR)were calculated.The degree of neurological impairment was assessed by National Institutes of Health Stroke Scale(NIHSS).The patients were divided into two groups of A(NIHSS score ≤ 5 points,60 cases)and B(NIHSS score>5 points,57 cases).The influencing factors for NIHSS score were analyzed by multiple linear regression analysis.Results The TC and LDL-C in group A were higher than those in group B,while hypersensitive C-reactive protein and NLR were lower than those in group B(P<0.05).TC and LDL-C were negatively correlated with NIHSS score(rs=-0.24 and-0.26,P<0.05),and D-dimer,NLR and WBC were positively correlated with NIHSS score(rs=0.19,0.20 and 0.19,P<0.05).Multiple linear regression analysis showed that D-dimer,NLR and fasting blood glucose were the influencing factors for NIHSS score in sICH patients(P<0.05).Conclusion Blood indicators are related to the degree of neurological impairment in sICH patients,and D-dimer,NLR and fasting blood glucose are the influencing factors.